Isco starts over Gareth Bale for Real Madrid in tonight's Champions League Final against Juventus, but Lucas Vazquez and James Rodriguez miss out completely.
Zinedine Zidane takes no chances over Bale's fitness, although his selection headache was made easier by the sparking form of Isco in the Welshman's absence.
Elsewhere, it is a full-strength Madrid line-up, with Dani Carvajal passed fit to make his first start at right-back since the end of April.
However, James appears to have played his last game for the capital giants as he is not even among their substitutes, while Lucas similarly fails to make the cut.
Juve are also boosted by having no first-team players unavailable, although Andrea Barzagli lines up in a three-man defence, consigning Juan Cuadrado to the bench.
Madrid are looking to become the first club in the modern era to defend the Champions League and the first Blancos side since 1958 to win a League and European cup double.
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Alves, Pjanic, Khedira, Alex Sandro; Dybala, Higuain, Mandzukic
Subs: Neto, Benatia, Lichtsteiner, Marchisio, Asamoah, Cuadrado, Lemina
Real Madrid: Keylor; Carvajal, Varane, Ramos, Marcelo; Modric, Casemiro, Kroos; Isco; Benzema, Ronaldo
Subs: Casilla, Nacho, Bale, Kovacic, Asensio, Morata, Danilo
Referee: Brych (GER)