Real Madrid ring the changes for the visit of Celta Vigo, with Asier Illarramendi the only survivor from midweek.
Los Blancos named a weakened line-up for Tuesday's 5-0 victory over Cornella in the Copa del Rey, but Isco's red card against Malaga last weekend means the former Real Sociedad man is allowed to keep his place in midfield.
Celta, meanwhile, suffered a shock 2-1 defeat to Segunda side Las Palmas in the Copa, and they too have opted to make widespread alterations, Gustavo Cabral and Pablo Hernandez the only remnants of the beaten team.
A Madrid win would see them equal the all-time Spanish record of 18 straight successes, set by Barcelona during the 2005-06 season.
Real Madrid: Casillas; Carvajal, Pepe, Ramos, Marcelo; Bale, Illarramendi, Kroos, James, Benzema, Ronaldo
Subs: Navas, Nacho, Arbeloa, Varane, Coentrao, Medran, Hernandez
Celta Vigo: Alvarez; Mallo, Cabral, Fontas, Jonny; Hernandez, Radoja, Krohn-Dehli; Orellana, Larrivey, Nolito
Subs: Ruben Blanco, Planas, Sergi Gomez, Alex Lopez, Augusto, Santi Mina, Charles
Referee: Alberto Undiano