Antoine Griezmann and Luciano Vietto start in attack for Atletico Madrid in the Champions League Round of 16 game at PSV Eindhoven.
Diego Simeone has Jan Oblak in goal and Juanfran, Diego Godin, Stefan Savic and Filipe Luis in his back four.
The midfield is made up of Gabi, Saul Niguez, Koke and Oliver Torres, and Griezmann and Vietto form the front two.
Winter signings Matias Kranevitter and Augusto Fernandez are on the bench awaiting their first taste of Champions League football, the latter after recovering from injury.
PSV meanwhile are without captain Luuk de Jong, who misses out through suspension, but do have ex-Deportivo La Coruna and Valencia midfielder Andres Guadardo fit.
The home side also include former Espanyol defender Hector Moreno, and are trained by Barcelona veteran Phillip Cocu.
PSV Eindhoven: Zoet; Arias, Bruma, Moreno, Willems; Guardardo, Propper, Van Ginkel; Narsingh, Pereiro, Locadia
Subs: Pasveer, Isimat, Schaars, Lestienne, Jozefzoon, Brenet, Hendrix
Atletico Madrid: Oblak; Juanfran, Godin, Savic, Filipe; Gabi, Saul, Koke, Oliver; Griezmann, Vietto
Subs: Moya, Gimenez, Gamez, Kranevitter, Augusto, Correa, Torres
Referee: Orsato [ITA]