Diego Simeone has called on both Diego Costa and David Villa for the visit of Sevilla.
Atletico Madrid are aiming to keep the pace with their city rivals after Real Madrid joined Atleti and Barca on 50 points with their 5-0 win over Betis on Saturday.
El Cholo has Thibaut Courtois in goal and Juanfran, Diego Godin, Miranda and Filipe Luis at left-back.
Gabi and Koke, fresh from agreeing a new contract, form the midfield axis while Turan Arda and Raul Garcia are also included.
Villa and Costa provide the goal threat for Simeone as Atletico will kick-off knowing the outcome of Barcelona’s trip to Levante.
Sevilla are chasing fourth place and Champions League qualification, with Unai Emery plumping for Carlos Bacca leading the line.
Beto is in goal for the visitors, behind a back four of Coke, Federico Fazio, Nico Pareja and Fernando Navarro.
Vicente Iborra and Dani Carrico start in the heart of midfield with captain Ivan Rakitic flanked by Alberto Moreno to the left and Vitolo to the right.
Atletico: Courtois; Juanfran, Godin, Miranda, Filipe; Gabi, Koke Arda, Raul Garcia; Villa, Diego Costa
Sevilla: Beto; Coke, Fazio, Pareja, Navarro; Iborra, Carrico; Vitolo, Rakitic, Moreno; Bacca