Barcelona are unchanged for the Clasico against a Real Madrid side who stick with a 4-4-2 diamond this afternoon.
Barca remain without Lionel Messi, Samuel Umtiti and Thomas Vermaelen, so Clement Lenglet continues alongside Gerard Pique in central defence.
Rafinha replaced Messi on the right wing against Inter midweek, opening the scoring in a 2-0 win, and he keeps his spot with Sergi Roberto behind him.
Madrid, meanwhile, have gone four Liga games without a win and came close to going their longest without a goal in 116 years of existence.
That has left Coach Julen Lopetegui hanging by a threat at the helm, and a defeat would surely result in his dismissal.
Los Blancos have problems in defence, with Jesus Vallejo joining Dani Carvajal on the treatment table, so Nacho Fernandez moves out to the right.
Lopetegui also retains the 4-4-2 diamond, regularly used by predecessor Zinedine Zidane, with Isco playing just off Gareth Bale and Karim Benzema in attack.
However, Vinicius Junior is nowhere to be seen in the matchday squad, despite the teenage striker choosing to travel with the first team over turning out for Castilla after his one-match ban was lifted.
Madrid have gone five Clasicos without a win, their last victory coming in April 2016, but the Catalans haven’t beaten their arch-rivals on home soil for three years.
This will be referee Jose Maria Sanchez Martinez’s second Clasico after he oversaw the Blaugrana’s 3-0 win at the Santiago Bernabeu last December.
Barcelona: Ter Stegen; Sergi Roberto, Pique, Lenglet, Alba; Rakitic, Busquets, Arthur; Rafinha, Suarez, Coutinho
Subs: Semedo, Dembele, Cillessen, Malcom, Munir, Arturo Vidal, Chumi
Real Madrid: Courtois; Nacho, Varane, Ramos, Marcelo; Modric, Casemiro, Kroos; Isco; Bale, Benzema
Subs: Keylor, Odriozola, Valverde, Ceballos, Asensio, Vazquez, Mariano
Referee: Sanchez Martinez