Iker Casillas has kept his place in the Spain starting XI, but Vicente del Bosque does make two changes from the team that lost to Netherlands.
Bayern Munich centre-back Javi Martinez plays at centre-back alongside Sergio Ramos, and Pedro comes in for Xavi, with Andres Iniesta moving back into the midfield three.
Despite his disappointing performances so far, Diego Costa starts up front with David Silva in support, whilst Xabi Alonso and Sergio Busquets also retain their places from the humiliation in Salvador.
Cesar Azpilicueta is at right-back, with Sergio Ramos and Jordi Alba completing the back four.
Jorge Sampaoli meanwhile, gives starts to Real Sociedad’s Claudio Bravo, Barcelona forward Alexis Sanchez and Valencia loanee Eduardo Vargas.
Spain: Casillas; Azpilicueta, Martínez, Ramos, Alba; Alonso, Busquets; Iniesta, Pedro, Silva; Costa
Chile: Bravo; Medel, Silva, Jara; Isla, Aránguiz, Díaz, Mena; Vidal; Sánchez, Vargas.
