Barcelona include Andres Iniesta in their starting eleven to face Eibar, who make one change from the side who beat Leganes.
Despite still being unbeaten so far this season, the Blaugrana have seen their lead at the top of La Liga cut to seven points after consecutive draws against Espanyol and Getafe.
It is perhaps with this in mind that veteran midfielder Iniesta has been included despite Tuesday’s Champions League last 16 first leg with Chelsea looming large on the horizon.
Lionel Messi, Luis Suarez, Sergio Busquets, Ivan Rakitic and Gerard Pique all start alongside Iniesta as Coach Ernesto Valverde looks to offer no further encouragement to Diego Simeone’s Atletico Madrid in the title race.
Philippe Coutinho drops to the bench after playing an hour of last weekend’s stalemate with Getafe at the Camp Nou.
The hosts, meanwhile, are looking to build upon their fine recent form, which has seen them go unbeaten in their last four matches and lose just one of their last 11 League fixtures.
Midfielder Joao Jordan comes in for forward Charles in the only change to the team who won late on at Leganes in the last round of fixtures.
A famous victory here would see the Basque side climb above Villarreal into sixth place in the table.
Kick-off at Ipurua is at 15.15 GMT.
Eibar: Dmitrovic, Peña, Ramis, Arbilla, Jose Angel, Dani Garcia, Pape Diop, Orellana, Jordan, Inui, Kike
Barcelona: Ter Stegen, Sergi Roberto, Pique, Umtiti, Jordi Alba, Paulinho, Rakitic, Busquets, Iniesta, Messi, Suarez