Philippe Coutinho is only a substitute for Barcelona against Valencia in tonight's Copa del Rey semi-final first leg.
Coutinho managed 66 minutes on his full Barca debut against Alaves last weekend, and he is replaced on the Catalans’ right wing by Aleix Vidal.
Elsewhere, Sergi Roberto and Jordi Alba come into into the full-back positions and Paulinho makes way for Sergio Busquets in central midfield.
Marcelino, meanwhile, rings the changes after Valencia's 4-1 home defeat to Real Madrid as Jaume Domenech, Gabriel Paulista, Ruben Vezo, Andreas Pereira, Carlos Soler and new boy Luciano Vietto are all summoned.
The two sides last met in November, when Alba rescued Barca a 1-1 draw, yet their previous Copa meeting at Camp Nou saw the Blaugrana demolish Los Che – then coached by Gary Neville – 7-0.
Barcelona: Cillessen; Sergi Roberto, Pique, Umtiti, Alba; Aleix Vidal, Rakitic, Busquets, Iniesta; Messi, Suarez
Subs: Ter Stegen, Denis, Coutinho, Paulinho, Alcacer, Digne, Mina
Valencia: Domenech; Montoya, Vezo, Gabriel Paulista, Gaya; Soler, Parejo, Coquelin, Pereira; Vietto, Moreno
Subs: Maksimovic, Zaza, Neto, Lato, Ferran, Santi Mina, Nacho Vidal
Referee: Sanchez Martinez