Lionel Messi, Luis Suarez and Neymar all start as Barcelona host Espanyol in a potential title-decider of a Catalan derby.
La Blaugrana could be crowned champions if they beat Los Periquitos, Atletico Madrid lose at Levante and Real Madrid do anything other than win at home to Valencia.
The three teams are separated by just one point ahead of the penultimate round of games, with Barca top, Atleti second and Madrid third.
Claudio Bravo was ruled out in midweek and duly doesn’t play, with Marc-Andre Ter Stegen taking the gloves behind a back four of Dani Alves, Gerard Pique, Javier Mascherano and Jordi Alba.
It’s Ivan Rakitic, Sergio Busquets and Andres Iniesta in midfield, with the MSN in full force in attack for birthday boy Luis Enrique.
Espanyol go with Pau Lopez in goal and he might get a frosty reception at Camp Nou after saying in midweek he didn’t care who wins the title, as long as it’s a Madrid team.
Javi Lopez, Enzo Roco, Oscar Duarte and Victor Alvarez form the back four protecting Lopez – hopefully just from the attacks of the Barca players, not the fans.
Jose Canas, Pape Diop and Victor Sanchez are Constantin Galca’s three-man midfield and Hernan Perez, Felipe Caicedo and Marco Asensio – on loan from Real Madrid – are the attack.
Barcelona: Ter Stegen; Alves, Pique, Mascherano, Alba; Busquets, Rakitic, Iniesta; Messi, Suarez, Neymar
Subs: Masip, Arda, Rafinha, Munir, Sergi Roberto, Vidal, Mathieu
Espanyol: Pau Lopez; Javi Lopez, Roco, Duarte, Alvarez; Canas, Dip, Sanchez; Perez, Caicedo, Asensio
Subs: Arlauskis, Lopez, Rober, Jordan, Montanes, Salva Sevilla, Gerard Moreno
Referee: Gil Manzano