Diego Simeone has named Jan Oblak in goal for the Champions League trip to Olympiakos, with Arda Turan also in the starting XI.
Oblak comes in for Miguel Angel Moya for his Atletico debut, having signed for the club over the summer from Benfica.
Moya, a summer signing from Getafe, had taken the gloves for the Spanish champions’ five games so far this season, two in the Supercopa de Espana and three in the League.
Turan returns to the starting team after a goal as a substitute in the weekend’s Madrid derby, while Cristian Ansaldi replaces Guilherme Siqueira at left-back and Mario Suarez replaces Tiago Mendes.
Olympiakos have Spaniards Roberto and Alberto Botia in their team and also include former Barcelona defender Eric Abidal.
Coach Michel also names the likes of Kostas Mitroglou, Alejandro Dominguez and Ibrahim Afellay, who is on loan from La Blaugrana.
Olympiakos: Roberto; Elabdellaoui, Abidal, Botia, Masuaku; Maniatis, Kasami; Domiguez, Milivojevic, Afellay; Mitroglou
Atletico Madrid: Oblak; Juanfran, Miranda, Godin, Ansaldi; Arda, Koke, Gabi, Mario; Raul Garcia, Mandzukic
Referee: Pedro Proenca (POR)