Barcelona have made four changes from the side that lost to Real Madrid in the Copa del Rey, as they prepare to face Athletic Bilbao.

The Blaugrana’s nightmare week could go from bad to worse this evening if they lost to the Basque outfit at Camp Nou.

A defeat tonight would almost certainly end their title ambitions, and as such, Tata Martino has gone with a front-three of Lionel Messi, Alexis Sanchez and Pedro.

Alex Song comes into midfield with Cesc Fabregas out, whilst Adriano plays at left-back in place of the injured Jordi Alba.

Los Leones meanwhile, have gone with an attacking XI led by Aritz Aduriz, Iker Muniain and Markel Susaeta.

Barcelona: Pinto; Alves, Bartra, Mascherano, Adriano; Xavi, Song, Iniesta; Alexis, Messi, Pedro

Athletic Bilbao: Iraizoz; De Marcos, San José, Laporte, Balenziaga; Iturraspe, Erik Moran, Herrera; Susaeta, Aduriz, Muniain