Sergio Busquets will play at centre-back as Barcelona prepare to take on Granada this evening.
The Blaugrana go to Andalusia looking for the three points that will take them to the top of the League.
And they will do so with the midfielder at the centre of defence alongside Javier Mascherano. Martin Montoya and Adriano play at full-back for an almost entirely makeshift back four.
Alex Song also starts in place of Xavi, with Cesc Fabregas and Andres Iniesta in the midfield three.
Pedro has been chosen ahead of Alexis Sanchez up front – Lionel Messi and Neymar partner the Spain international.
El Grana meanwhile, name a relatively attacking line-up led by Piti and Yussef El-Arabi.
Granada: Karnezis, Nyom, Ilori, Murillo, Foulquier; Iturra, Fran Rico, Recio; Brahimi, Piti, El Arabi
Barcelona: Pinto, Montoya, Busquets, Mascherano, Adriano, Song, Cesc, Iniesta, Pedro, Messi, Neymar