Lionel Messi returns to the Barcelona side as La Blaugrana face Roma having already had their progress in the Champions League confirmed.
Bayer Leverkusen’s draw with BATE Borisov in an early Tuesday kick-off means the Catalans can’t finish lower than second and will seal first with a draw.
Messi missed two months’ of playing time after he was injured against Las Palmas late in September, returning from the bench in Barca’s weekend win over Real Madrid.
Former Roma Coach Luis Enrique has restored the trident of Messi, Neymar and Luis Suarez and made a handful of other changes from the team that beat Los Blancos.
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