Espanyol make the trip to Andalusia to face Real Betis, having chalked up only one point from their four Primera Liga openers.
The Periquitos have drawn once and lost three times so far in La Liga, but centre-back Raul Rodriguez is confident a win will come soon.
“Three points will come if we keep playing well. The team has changed considerably since the start of the season. We are optimistic and will continue to fight for three points.
“The way the team is playing does not correspond with the results we've been getting.”
Kick-off: Saturday, 21 September, 6:00pm (UK time)