| Week 1 | 19-Aug-2012 | Week 2 | 26-Aug-2012 | |||
| Athletic Bilbao | – | Real Betis | Real Betis | – | Rayo Vallecano | |
| Levante | – | Atletico Madrid | Atletico Madrid | – | Athletic Bilbao | |
| Real Zaragoza | – | Real Valladolid | Real Valladolid | – | Levante | |
| Mallorca | – | Espanyol | Espanyol | – | Real Zaragoza | |
| Celta Vigo | – | Malaga | Malaga | – | Mallorca | |
| Barcelona | – | Real Sociedad | Real Sociedad | – | Celta Vigo | |
| Deportivo | – | Osasuna | Osasuna | – | Barcelona | |
| Real Madrid | – | Valencia | Valencia | – | Deportivo | |
| Sevilla | – | Getafe | Getafe | – | Real Madrid | |
| Rayo Vallecano | – | Granada | Granada | – | Sevilla | |
| Week 3 | 26-Aug-2012 | Week 4 | 16-Sep-2012 | |||
| Real Betis | – | Atletico Madrid | Atletico Madrid | – | Rayo Vallecano | |
| Athletic Bilbao | – | Real Valladolid | Real Valladolid | – | Real Betis | |
| Levante | – | Espanyol | Espanyol | – | Athletic Bilbao | |
| Real Zaragoza | – | Malaga | Malaga | – | Levante | |
| Mallorca | – | Real Sociedad | Real Sociedad | – | Real Zaragoza | |
| Celta Vigo | – | Osasuna | Osasuna | – | Mallorca | |
| Barcelona | – | Valencia | Valencia | – | Celta Vigo | |
| Deportivo | – | Getafe | Getafe | – | Barcelona | |
| Real Madrid | – | Granada | Granada | – | Deportivo | |
| Rayo Vallecano | – | Sevilla | Sevilla | – | Real Madrid | |
| Week 5 | 23-Sep-2012 | Week 6 | 30-Sep-2012 | |||
| Atletico Madrid | – | Real Valladolid | Real Valladolid | – | Rayo Vallecano | |
| Real Betis | – | Espanyol | Espanyol | – | Atletico Madrid | |
| Athletic Bilbao | – | Malaga | Malaga | – | Real Betis | |
| Levante | – | Real Sociedad | Real Sociedad | – | Athletic Bilbao | |
| Real Zaragoza | – | Osasuna | Osasuna | – | Levante | |
| Mallorca | – | Valencia | Valencia | – | Real Zaragoza | |
| Celta Vigo | – | Getafe | Getafe | – | Mallorca | |
| Barcelona | – | Granada | Granada | – | Celta Vigo | |
| Deportivo | – | Sevilla | Sevilla | – | Barcelona | |
| Rayo Vallecano | – | Real Madrid | Real Madrid | – | Deportivo | |
| Week 7 | 07-Oct-2012 | Week 8 | 21-Oct-2012 | |||
| Real Valladolid | – | Espanyol | Espanyol | – | Rayo Vallecano | |
| Atletico Madrid | – | Malaga | Malaga | – | Real Valladolid | |
| Real Betis | – | Real Sociedad | Real Sociedad | – | Atletico Madrid | |
| Athletic Bilbao | – | Osasuna | Osasuna | – | Real Betis | |
| Levante | – | Valencia | Valencia | – | Athletic Bilbao | |
| Real Zaragoza | – | Getafe | Getafe | – | Levante | |
| Mallorca | – | Granada | Granada | – | Real Zaragoza | |
| Celta Vigo | – | Sevilla | Sevilla | – | Mallorca | |
| Barcelona | – | Real Madrid | Real Madrid | – | Celta Vigo | |
| Rayo Vallecano | – | Deportivo | Deportivo | – | Barcelona | |
| Week 9 | 28-Oct-2012 | Week 10 | 04-Nov-2012 | |||
| Espanyol | – | Malaga | Malaga | – | Rayo Vallecano | |
| Real Valladolid | – | Real Sociedad | Real Sociedad | – | Espanyol | |
| Atletico Madrid | – | Osasuna | Osasuna | – | Real Valladolid | |
| Real Betis | – | Valencia | Valencia | – | Atletico Madrid | |
| Athletic Bilbao | – | Getafe | Getafe | – | Real Betis | |
| Levante | – | Granada | Granada | – | Athletic Bilbao | |
| Real Zaragoza | – | Sevilla | Sevilla | – | Levante | |
| Mallorca | – | Real Madrid | Real Madrid | – | Real Zaragoza | |
| Celta Vigo | – | Deportivo | Deportivo | – | Mallorca | |
| Rayo Vallecano | – | Barcelona | Barcelona | – | Celta Vigo | |
| Week 11 | 11-Nov-2012 | Week 12 | 18-Nov-2012 | |||
| Malaga | – | Real Sociedad | Real Sociedad | – | Rayo Vallecano | |
| Espanyol | – | Osasuna | Osasuna | – | Malaga | |
| Real Valladolid | – | Valencia | Valencia | – | Espanyol | |
| Atletico Madrid | – | Getafe | Getafe | – | Real Valladolid | |
| Real Betis | – | Granada | Granada | – | Atletico Madrid | |
| Athletic Bilbao | – | Sevilla | Sevilla | – | Real Betis | |
| Levante | – | Real Madrid | Real Madrid | – | Athletic Bilbao | |
| Real Zaragoza | – | Deportivo | Deportivo | – | Levante | |
| Mallorca | – | Barcelona | Barcelona | – | Real Zaragoza | |
| Rayo Vallecano | – | Celta Vigo | Celta Vigo | – | Mallorca | |
| Week 13 | 25-Nov-2012 | Week 14 | 02-Dec-2012 | |||
| Real Sociedad | – | Osasuna | Osasuna | – | Rayo Vallecano | |
| Malaga | – | Valencia | Valencia | – | Real Sociedad | |
| Espanyol | – | Getafe | Getafe | – | Malaga | |
| Real Valladolid | – | Granada | Granada | – | Espanyol | |
| Atletico Madrid | – | Sevilla | Sevilla | – | Real Valladolid | |
| Real Betis | – | Real Madrid | Real Madrid | – | Atletico Madrid | |
| Athletic Bilbao | – | Deportivo | Deportivo | – | Real Betis | |
| Levante | – | Barcelona | Barcelona | – | Athletic Bilbao | |
| Real Zaragoza | – | Celta Vigo | Celta Vigo | – | Levante | |
| Rayo Vallecano | – | Mallorca | Mallorca | – | Real Zaragoza | |
| Week 15 | 09-Dec-2012 | Week 16 | 16-Dec-2012 | |||
| Osasuna | – | Valencia | Valencia | – | Rayo Vallecano | |
| Real Sociedad | – | Getafe | Getafe | – | Osasuna | |
| Malaga | – | Granada | Granada | – | Real Sociedad | |
| Espanyol | – | Sevilla | Sevilla | – | Malaga | |
| Real Valladolid | – | Real Madrid | Real Madrid | – | Espanyol | |
| Atletico Madrid | – | Deportivo | Deportivo | – | Real Valladolid | |
| Real Betis | – | Barcelona | Barcelona | – | Atletico Madrid | |
| Athletic Bilbao | – | Celta Vigo | Celta Vigo | – | Real Betis | |
| Levante | – | Mallorca | Mallorca | – | Athletic Bilbao | |
| Rayo Vallecano | – | Real Zaragoza | Real Zaragoza | – | Levante | |
| Week 17 | 22-Dec-2012 | Week 18 | 06-Jan-2013 | |||
| Valencia | – | Getafe | Rayo Vallecano | – | Getafe | |
| Osasuna | – | Granada | Granada | – | Valencia | |
| Real Sociedad | – | Sevilla | Sevilla | – | Osasuna | |
| Malaga | – | Real Madrid | Real Madrid | – | Real Sociedad | |
| Espanyol | – | Deportivo | Deportivo | – | Malaga | |
| Real Valladolid | – | Barcelona | Barcelona | – | Espanyol | |
| Atletico Madrid | – | Celta Vigo | Celta Vigo | – | Real Valladolid | |
| Real Betis | – | Mallorca | Mallorca | – | Atletico Madrid | |
| Athletic Bilbao | – | Real Zaragoza | Real Zaragoza | – | Real Betis | |
| Rayo Vallecano | – | Levante | Levante | – | Athletic Bilbao | |
| Week 19 | 13-Jan-2013 | Week 20 | 20-Jan-2013 | |||
| Getafe | – | Granada | Real Betis | – | Athletic Bilbao | |
| Valencia | – | Sevilla | Atletico Madrid | – | Levante | |
| Osasuna | – | Real Madrid | Real Valladolid | – | Real Zaragoza | |
| Real Sociedad | – | Deportivo | Espanyol | – | Mallorca | |
| Malaga | – | Barcelona | Malaga | – | Celta Vigo | |
| Espanyol | – | Celta Vigo | Real Sociedad | – | Barcelona | |
| Real Valladolid | – | Mallorca | Osasuna | – | Deportivo | |
| Atletico Madrid | – | Real Zaragoza | Valencia | – | Real Madrid | |
| Real Betis | – | Levante | Getafe | – | Sevilla | |
| Athletic Bilbao | – | Rayo Vallecano | Granada | – | Rayo Vallecano | |
| Week 21 | 27-Jan-2013 | Week 22 | 03-Feb-2013 | |||
| Rayo Vallecano | – | Real Betis | Atletico Madrid | – | Real Betis | |
| Athletic Bilbao | – | Atletico Madrid | Real Valladolid | – | Athletic Bilbao | |
| Levante | – | Real Valladolid | Espanyol | – | Levante | |
| Real Zaragoza | – | Espanyol | Malaga | – | Real Zaragoza | |
| Mallorca | – | Malaga | Real Sociedad | – | Mallorca | |
| Celta Vigo | – | Real Sociedad | Osasuna | – | Celta Vigo | |
| Barcelona | – | Osasuna | Valencia | – | Barcelona | |
| Deportivo | – | Valencia | Getafe | – | Deportivo | |
| Real Madrid | – | Getafe | Granada | – | Real Madrid | |
| Sevilla | – | Granada | Sevilla | – | Rayo Vallecano | |
| Week 23 | 10-Feb-2013 | Week 24 | 17-Feb-2013 | |||
| Rayo Vallecano | – | Atletico Madrid | Real Valladolid | – | Atletico Madrid | |
| Real Betis | – | Real Valladolid | Espanyol | – | Real Betis | |
| Athletic Bilbao | – | Espanyol | Malaga | – | Athletic Bilbao | |
| Levante | – | Malaga | Real Sociedad | – | Levante | |
| Real Zaragoza | – | Real Sociedad | Osasuna | – | Real Zaragoza | |
| Mallorca | – | Osasuna | Valencia | – | Mallorca | |
| Celta Vigo | – | Valencia | Getafe | – | Celta Vigo | |
| Barcelona | – | Getafe | Granada | – | Barcelona | |
| Deportivo | – | Granada | Sevilla | – | Deportivo | |
| Real Madrid | – | Sevilla | Real Madrid | – | Rayo Vallecano | |
| Week 25 | 24-Feb-2013 | Week 26 | 03-Mar-2013 | |||
| Rayo Vallecano | – | Real Valladolid | Espanyol | – | Real Valladolid | |
| Atletico Madrid | – | Espanyol | Malaga | – | Atletico Madrid | |
| Real Betis | – | Malaga | Real Sociedad | – | Real Betis | |
| Athletic Bilbao | – | Real Sociedad | Osasuna | – | Athletic Bilbao | |
| Levante | – | Osasuna | Valencia | – | Levante | |
| Real Zaragoza | – | Valencia | Getafe | – | Real Zaragoza | |
| Mallorca | – | Getafe | Granada | – | Mallorca | |
| Celta Vigo | – | Granada | Sevilla | – | Celta Vigo | |
| Barcelona | – | Sevilla | Real Madrid | – | Barcelona | |
| Deportivo | – | Real Madrid | Deportivo | – | Rayo Vallecano | |
| Week 27 | 10-Mar-2013 | Week 28 | 17-Mar-2013 | |||
| Rayo Vallecano | – | Espanyol | Malaga | – | Espanyol | |
| Real Valladolid | – | Malaga | Real Sociedad | – | Real Valladolid | |
| Atletico Madrid | – | Real Sociedad | Osasuna | – | Atletico Madrid | |
| Real Betis | – | Osasuna | Valencia | – | Real Betis | |
| Athletic Bilbao | – | Valencia | Getafe | – | Athletic Bilbao | |
| Levante | – | Getafe | Granada | – | Levante | |
| Real Zaragoza | – | Granada | Sevilla | – | Real Zaragoza | |
| Mallorca | – | Sevilla | Real Madrid | – | Mallorca | |
| Celta Vigo | – | Real Madrid | Deportivo | – | Celta Vigo | |
| Barcelona | – | Deportivo | Barcelona | – | Rayo Vallecano | |
| Week 29 | 31-Mar-2013 | Week 30 | 07-Apr-2013 | |||
| Rayo Vallecano | – | Malaga | Real Sociedad | – | Malaga | |
| Espanyol | – | Real Sociedad | Osasuna | – | Espanyol | |
| Real Valladolid | – | Osasuna | Valencia | – | Real Valladolid | |
| Atletico Madrid | – | Valencia | Getafe | – | Atletico Madrid | |
| Real Betis | – | Getafe | Granada | – | Real Betis | |
| Athletic Bilbao | – | Granada | Sevilla | – | Athletic Bilbao | |
| Levante | – | Sevilla | Real Madrid | – | Levante | |
| Real Zaragoza | – | Real Madrid | Deportivo | – | Real Zaragoza | |
| Mallorca | – | Deportivo | Barcelona | – | Mallorca | |
| Celta Vigo | – | Barcelona | Celta Vigo | – | Rayo Vallecano | |
| Week 31 | 14-Apr-2013 | Week 32 | 21-Apr-2013 | |||
| Rayo Vallecano | – | Real Sociedad | Osasuna | – | Real Sociedad | |
| Malaga | – | Osasuna | Valencia | – | Malaga | |
| Espanyol | – | Valencia | Getafe | – | Espanyol | |
| Real Valladolid | – | Getafe | Granada | – | Real Valladolid | |
| Atletico Madrid | – | Granada | Sevilla | – | Atletico Madrid | |
| Real Betis | – | Sevilla | Real Madrid | – | Real Betis | |
| Athletic Bilbao | – | Real Madrid | Deportivo | – | Athletic Bilbao | |
| Levante | – | Deportivo | Barcelona | – | Levante | |
| Real Zaragoza | – | Barcelona | Celta Vigo | – | Real Zaragoza | |
| Mallorca | – | Celta Vigo | Mallorca | – | Rayo Vallecano | |
| Week 33 | 28-Apr-2013 | Week 34 | 05-May-2013 | |||
| Rayo Vallecano | – | Osasuna | Valencia | – | Osasuna | |
| Real Sociedad | – | Valencia | Getafe | – | Real Sociedad | |
| Malaga | – | Getafe | Granada | – | Malaga | |
| Espanyol | – | Granada | Sevilla | – | Espanyol | |
| Real Valladolid | – | Sevilla | Real Madrid | – | Real Valladolid | |
| Atletico Madrid | – | Real Madrid | Deportivo | – | Atletico Madrid | |
| Real Betis | – | Deportivo | Barcelona | – | Real Betis | |
| Athletic Bilbao | – | Barcelona | Celta Vigo | – | Athletic Bilbao | |
| Levante | – | Celta Vigo | Mallorca | – | Levante | |
| Real Zaragoza | – | Mallorca | Real Zaragoza | – | Rayo Vallecano | |
| Week 35 | 12-May-2013 | Week 36 | 19-May-2013 | |||
| Rayo Vallecano | – | Valencia | Getafe | – | Valencia | |
| Osasuna | – | Getafe | Granada | – | Osasuna | |
| Real Sociedad | – | Granada | Sevilla | – | Real Sociedad | |
| Malaga | – | Sevilla | Real Madrid | – | Malaga | |
| Espanyol | – | Real Madrid | Deportivo | – | Espanyol | |
| Real Valladolid | – | Deportivo | Barcelona | – | Real Valladolid | |
| Atletico Madrid | – | Barcelona | Celta Vigo | – | Atletico Madrid | |
| Real Betis | – | Celta Vigo | Mallorca | – | Real Betis | |
| Athletic Bilbao | – | Mallorca | Real Zaragoza | – | Athletic Bilbao | |
| Levante | – | Real Zaragoza | Levante | – | Rayo Vallecano | |
| Week 37 | 29-May-2013 | Week 38 | 01-Jun-2013 | |||
| Getafe | – | Rayo Vallecano | Granada | – | Getafe | |
| Valencia | – | Granada | Sevilla | – | Valencia | |
| Osasuna | – | Sevilla | Real Madrid | – | Osasuna | |
| Real Sociedad | – | Real Madrid | Deportivo | – | Real Sociedad | |
| Malaga | – | Deportivo | Barcelona | – | Malaga | |
| Espanyol | – | Barcelona | Celta Vigo | – | Espanyol | |
| Real Valladolid | – | Celta Vigo | Mallorca | – | Real Valladolid | |
| Atletico Madrid | – | Mallorca | Real Zaragoza | – | Atletico Madrid | |
| Real Betis | – | Real Zaragoza | Levante | – | Real Betis | |
| Athletic Bilbao | – | Levante | Rayo Vallecano | – | Athletic Bilbao | |
