Real Madrid boss Zinedine Zidane makes two changes from the side that drew 0-0 with rival Atletico Madrid at the weekend.
Luka Modric is back from injury, and he comes into midfield to replace Fede Valverde, with Lucas Vazquez starts in place of Gareth Bale in attack.
Club Brugges, who are currently top of the Belgian Division 1, also make two changes from their 5-0 win at Mechelen.
Manager Philippe Clement brings in Federico Ricca and Dennis Bonaventure in place of Eduard Sobol and David Okereke.
REAL MADRID: Courtois, Carvajal, Ramos, Varane, Nacho, Modric, Casemiro, Kroos, Hazard, Benzema, Vazquez
SUBS: Areola, Militao, Marcelo, Valverde, Jovic, Isco, Vinicius
CLUB BRUGGES: Mignolet, Lourenco, Mechele, Deli, Ricca, Vormer, Rits, Vanaken, Diatta, Bonaventure,Tau
SUBS: Horvath, Sobol, Kossounou, Diagne, Schrijvers, Cools, P
