Real Madrid boss Zinedine Zidane makes just one change from the side that lost 3-0 to PSG in the Champions League.
Skipper Sergio Ramos returns to the defence in place of Brazilian international Eder Militao.
Former Real Madrid boss Julen Lopetegui also rings the changes for Sevilla CF, with just two players remaining from the side that won away at FK Qarabag in the Europa League.
With goal keeper Thomas Vaclik and Diego Carlos keeping their places.
SEVILLA CF: Vaclik, Navas, Carrico, Carlos, Reguilon, Banega, Fernando, Jordan, Ocampos, De Jong, Vazquez
SUBS: Bonou, Kounde, Nolio, Hernandez, Gudelj, Escudero, Torres
REAL MADRID: Courtois, Carvajal, Ramos, Varane, Mendy, Kroos, Casemiro, Rodriguez, Bale, Benzema, Hazard
SUBS: Areola, Militao, Nacho, Valverde, Vazquez, Jovic, Vinicius