Spain host Sweden at the Santiago Bernabeu in their final UEFA European Championships clash of 2018-19.
Roberto Moreno continues to stand in for Luis Enrique, and La Roja make wholesale changes from the 4-1 win the Faroe Islands at the weekend.
Only Kepa Arrizabalaga, skipper Sergio Ramos and Real Madrid team mate keep their starting XI places for the visit of Janne Andersson's side.
Sweden, who won 3-0 at home to Malta at the weekend, make just one change to that team, with veteran midfielder Sebastien Larsson replacing Kristoffer Olsson.
SPAIN: Kepa, Carvajal, Ramos, Martinez, Alba, Busquets, Parejo, Ruiz, Asensio, Rodrigo, Isco
SUBS: De Gea, Lopez, Hermoso, Llorente, Gaya, Rodri, Cazorla, Roberto, Morata, Aspas, Navas, Ozarzabal
SWEDEN: Olsen, Lustig, Helander, Jansson, Augustinsson, Larsson, Ekdal, Forsberg, Claesson, Berg, Quaison
SUBS: Svensson, Johansson, Nordfeldt, Karlsson, Olsson, Andersson, Johnsson, Durmaz, Hult, Guidetti, Krafth, Isak