Jasper Cillessen has been handed a first La Liga appearance of the season, in what is likely to be the Dutchman's farewell appearance for Barcelona.
Ernesto Valverde makes three changes from the side that lost 4-0 at Liverpool in th Champions League in midweek, with Cillessen replacing Marc Ter Stegen in goal, for the evisit of Getafe.
Luis Suarez is out, after undergoing knee surgery earlier this week, with Brazilian Malcom coming in for him - while Samuel Umtiti replaces his French international colleague Clement Lenglet in defence.
Getafe boss Jose Bordalas makes one change from the side that won 2-0 at home to Girona last weekend, with Gaku Shibasaki in for Jaime Mata .
BARCELONA: Cillessen, Roberto, Pique, Umtiti, Alba, Busquets, Rakitic, Vidal, Coutinho, Messi, Malcom
SUBS: Ter Stegen, Semedo, Todibo, Lenglet, Alena, Puig, Ruiz
GETAFE: Soria, Suarez, Djene, Cabrera, Olivera, Fouliquier, Maksimovic, Arambarri, Shibasaki, Angel, Molina
SUBS: Chichizola, Portillo, Alonso, Pepe, Flamini, Miguel, Duro