Atletico Madrid welcome back Diego Costa and Jan Oblak against Athletic Bilbao, while the visitors will be without Aritz Aduriz and Raul Garcia.
The Spanish international striker and Slovenian shot-stopper were both unavailable for Thursday’s 4-1 win at FC Copenhagen due to injuries but have since recovered.
Aduriz – who netted twice against Spartak Moscow on Thursday – is suspended while former Atletico midfielder Garcia misses out against his old club.
Atletico boss Diego Simeone confirmed the returns of Oblak and Costa before remarking on Aduriz’s absence: “They will lose aerial power, but we must be wary of the pace they have up front.
“Inaki Williams is extremely dangerous and we usually press high, so there will be space in behind that we must be on our guard against.”