Juventus midfield duo Sami Khedira and Claudio Marchisio will both be unavailable for the trip to Barcelona on Tuesday.
The Bianconeri’s Coach Max Allegri has confirmed his side will be without the central midfielders while Alex Sandro, Giorgio Chiellini and Mario Mandzukic will all face late fitness tests.
“Khedira and Marchisio are definitely out,” Allegri told reporters.
“Khedira came back from international duty, where he had a knock to the knee, rested for a few days and then played 30 minutes.
“The following day, he felt pain again. Essentially, it will take a week or so to have him back.”
Sandro is recovering from an illness, Chiellini returned to training on Sunday while Mandzukic picked up a knock against Chievo on Saturday.
See the latest La Liga predictions and betting tips with Eurotips.co.uk