Barcelona could welcome back Andres Iniesta, Gerard Pique, Carles Puyol, Adriano and Sergio Busquets for El Clasico a week on Sunday.
Coach Tito Vilanova is hoping to have all of them fit for the crunch match against the reigning champions on October 7, according to AS.
Iniesta – who suffered a hamstring strain on international duty – is to travel with the squad for the Sevilla game on Saturday, and could come off the bench if needed. He should play at least 45 minutes in the Champions League game against Benfica next Tuesday, in order to regain some match fitness ahead of the match with Jose Mourinho's side.
Pique is the least likely of the five to make the Camp Nou showdown. The 25-year-old defender limped out against Spartak Moscow last week with a foot injury, and will miss the Sevilla and Benfica games.
Captain Puyol has been out for some time with a knee injury, but is hopeful of making the squad for the visit of the Merengues.
Adriano and Busquets are recovering from a muscle strain and back pain respectively.
