La Blaugrana head to the Estadio Mestalla looking to edge back into the Champions League spots with a La Liga win against Los Che and the Uruguayan is expected to start.
Araujo missed the midweek Europa League 1-1 draw with Napoli due to a calf problem and he is expected to replace the suspended Gerard Pique in central defence.
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Skipper Sergio Busquets is expected to come back into midfield but Xavi faces a conundrum over his attacking options.
If Xavi does opt to rotate, Dutch forward Luuk de Jong looks to be the most likely change, in place of Aubameyang.