Los Rojiblancos are trailing 1-0 from their first leg defeat to Thomas Tuchel’s side ahead of their trip to Stamford Bridge this week.
However, as per reports from Diario AS, Simeone’s plans in training this week have indicated he will will reshuffle his starting team against the Premier League side.
Renan Lodi is set to replace Mario Hermoso at left back with Geoffrey Kondogbia in for Saul Niguez as part of a pair of changes from their 0-0 La Liga draw away at Getafe last weekend.
POSSIBLE ATLETICO MADRID STARTING XI V CHELSEA
Oblak; Trippier, Savic, Gimenez, Lodi; Koke, Kondogbia, Llorente, Carrasco; Suarez, Felix