Villarreal saw more of the ball and were sharper in their passing, but Sevilla were far more clinical and effective in the final third.
The hosts took the lead inside the first ten minutes through Lucas Ocampos. The Argentine wide-man converted a penalty with ease after Juan Foyth was judged to have handled the ball in the box after a VAR review.
Then, eight minutes after the second-half got underway, Sevilla doubled their lead. The Andalusians broke quickly after successfully defending an away attack, before Ocampos slid through Moroccan forward Youssef En-Nesyri to finish coolly.