Rodrigo Moreno and Isco lead the line for Spain against Germany in this evening's World Cup dress rehearsal.
Isco is likely to join David Silva in flanking lone striker Rodrigo, who has scored four goals in his last three games for Valencia.
Elsewhere, Julen Lopetegui names a full-strength back five, with David de Gea in goal, Gerard Pique partnering Sergio Ramos in central defence and Dani Carvajal and Jordi Alba both out wide.
Sergio Busquets is absent in central midfield due to a toe injury, so Koke sits in for the Barcelona man, supporting Thiago Alcantara and Andres Iniesta.
Germany, meanwhile, spring no surprises as Real Madrid midfielder Toni Kroos starts and Barcelona shot-stopper Marc-Andre ter Stegen continues to deputise for the crocked Manuel Neuer.
The two nations have met 22 times in the past, with La Roja winning on seven occasions, including in the semi-finals of Euro 2008 and the 2010 World Cup.
Germany: Ter Stegen; Kimmich, Boateng, Hummels, Hector; Khedira, Kroos; Muller, Ozil, Draxler; Werner
Subs: Leno, Sane, Brandt, Trapp, Plattenhardt, Stindl, Mario Gomez, Can, Ginter, Goretzka, Wagner, Rudy, Gundogan, Rudiger, Sule
Spain: De Gea; Carvajal, Pique, Ramos, Alba; Thiago, Koke, Iniesta; Silva, Rodrigo, Isco
Subs: Costa, Saul, Vazquez, Asensio, Aspas, Odriozola, Kepa, Rodri, Parejo, Nacho, Reina, Azpilicueta, Marcos Alonso
Referee: Collum (SCO)