Sevilla are without Jesus Navas for tonight's Champions League last-16 second leg as Manchester United only name Paul Pogba as a substitute.
A calf injury rules Navas out of a return to Manchester, where he spent four years with Pep Guardiola's City, while no chances are taken over Pogba, the Frenchman having picked up a knock against Liverpool last weekend.
Sebastian Corchia joins his fellow right-sider on the sidelines, but Vincenzo Montella is able to call on the rest of his squad, with Luis Muriel again preferred to Wissam Ben Yedder up top.
The Red Devils, meanwhile, come into the match on the back of three straight wins and pile on the pace as Jesse Lingard, Marcus Rashford and Alexis Sanchez support lone striker Romelu Lukaku.
The tie is finely poised from the first leg, which ended 0-0 a fortnight ago.
Manchester United: De Gea; Valencia, Bailly, Smalling, Young; Fellaini, Matic; Lingard, Alexis, Rashford; Lukaku
Subs: Lindelof, Pogba, Mata, Martial, Romero, Darmian, McTominay
Sevilla: Sergio Rico; Mercado, Kjaer, Lenglet, Escudero; Sarabia, N'Zonzi, Banega, Correa; Franco Vazquez; Muriel
Subs: Arana, Ben Yedder, Geis, Soria, Pizarro, Pareja, Nolito
Referee: Makkelie (NED)