Toni Kroos and Luka Modric are facing a race against time to be fit for the Champions League return leg against Paris Saint-Germain.
The central midfield duo did not participate in training with the rest of the first-team squad on Friday, although Zinedine Zidane received a boost with Marcelo’s return to the fold.
None will be involved in Saturday’s La Liga clash against Getafe with Casemiro, Marcos Llorente and Matteo Kovacic likely to feature.
Game-time may also be given to Dani Ceballos, while Isco is an also an option should Zidane opt to start with a more attack-minded formation.
Central defender Jesus Vallejo has also returned to fitness while youth-team midfielder Oscar Rodriguez is also included in the matchday squad.