Kepa Arrizabalaga debuts in goal for Spain against Costa Rica, who are without Real Madrid's Keylor Navas between the sticks.
Kepa is considered to be Spain's biggest goalkeeping prospect, and the Athletic Bilbao starlet is given the chance to showcase his potential ahead of David de Gea and Pepe Reina.
Elsewhere, Alvaro Odriozola returns at right-back after chipping in with an assist against Albania last month – that 3-0 victory sending La Roja to next summer's World Cup.
Other than the Basque pair, however, it is a full-strength XI picked by Julen Lopetegui as Costa Rica – their opponents at La Rosaleda – will join them in Russia.
Yet Alvaro Morata will not be pitting his wits against his former Madrid teammate, who is still recovering from a thigh injury. His place is taken by the aptly-named Danny Carvajal.
La Roja have played the Central Americans twice before and never lost to them, drawing their first meeting 2-2, before winning the second 2-1.
Spain: Kepa; Odriozola, Pique, Ramos, Alba; Thiago, Busquets, Iniesta; Silva, Morata, Isco
Subs: Illarramendi, Asensio, Saul, Reina, Aspas, Moreno, Rodrigo, De Gea, Nacho, Suso, Luis Alberto, Vitolo, Bartra, Callejon
Costa Rica: Danny Carvajal; Gamboa, Waston, Duarte, Calvo, Oviedo; Bolanos, Borges, Tejeda, Venegas; Urena
Subs: G Gonzalez, Gutierrez, Colindres, Moreira, O Rodriguez, Pemberton, Matarrita, Ortiz, Segura, Wallace
Referee: Sidiropoulos (GRE)