Spain have been paired with Italy, Israel, Albania, Macedonia and Liechtenstein in their qualifying group for the 2018 World Cup.
The most notable party facing La Roja in Group B is the Azzurri, whom they beat 4-0 in the Euro 2012 final three years ago.
Italy were demoted to Pot 2 in the draw following their 1-0 friendly defeat to Portugal in June.
Spain, meanwhile, will want to fare significantly better in Russia, having conceded their 2010 title last summer via a humiliating group-stage exit.
Group A: Netherlands, France, Sweden, Bulgaria, Belarus, Luxembourg
Group B: Portugal, Switzerland, Hungary, Faroe Islands, Latvia, Andorra
Group C: Germany, Czech Republic, Northern Ireland, Norway, Azerbaijan, San Marino
Group D: Wales, Austria, Serbia, Republic of Ireland, Moldova, Georgia
Group E: Romania, Denmark, Poland, Montenegro, Armenia, Kazakhstan
Group F: England, Slovakia, Scotland, Slovenia, Lithuania, Malta
Group G: Spain, Italy, Albania, Israel, Macedonia, Liechtenstein
Group H: Belgium, Bosnia-Herzegovina, Greece, Estonia, Cyprus
Group I: Croatia, Iceland, Ukraine, Turkey, Finland