Villarreal will be without Denis Cheryshev against Real Madrid as they would have to pay to field the on-loan Los Blancos winger.
Marca reports a fee of more than €200,000 would be needed to allow the Yellow Submarine to name the 23-year-old, as per the terms of his loan agreement.
Rayo Vallecano fell victim to the same stipulations a week earlier as they lost to Villarreal, when the Madrid team had to go without Jonathan Pereira and Javier Aquino, who are both on loan from El Madrigal.