Karim Benzema is fit to start for Real Madrid while Barcelona include Neymar and Cesc Fabregas.
Benzema was a doubt for the Clasico after suffering an injury in Madrid’s last La Liga outing, the 1-0 win over Malaga and missed the midweek Champions League game against Schalke.
But the France international has been passed fit to start against Barca and will again be joined by Gareth Bale and Cristiano Ronaldo in Carlo Ancelotti’s three-pronged attack.
It’s as expected in the rest of the Madrid team – Diego Lopez continues in goal with Dani Carvajal, Pepe, Sergio Ramos and Marcelo in the back four.
Xabi Alonso, Luka Modric and Angel Di Maria form the midfield with the so-called ‘BBC’ up front.
Tata Martino plumps for Neymar and Andres Iniesta over Pedro and Alexis Sanchez to join with Lionel Messi in attack.
Victor Valdes plays behind a back four of Dani Alves, Gerard Pique, Javier Mascherano and Jordi Alba with Sergio Busquets and Xavi Hernandez in midfield with Cesc.
Pedro and Alexis were started Barca’s last game, the 7-0 win over Osasuna, but Martino has returned to the XI that beat Manchester City at Camp Nou.
Real Madrid: Diego Lopez; Carvajal, Pepe, Ramos, Marcelo; Alonso, Modric, Di Maria; Bale, Benzema, Ronaldo
Barcelona: Valdes; Alves, Pique, Mascherano, Alba; Xavi, Busquets, Cesc; Neymar, Messi, Iniesta