Jordi Alba is missing for Barcelona, who switch back to 4-3-3 for tonight’s Champions League match against Olympiakos.
Barca confirmed on Tuesday that Alba had suffered a thigh injury in training, without specifying a date for his return.
Consequently, Lucas Digne is drafted in at left-back, with Sergi Roberto also coming in for Nelson Semedo on the right.
Elsewhere, Gerard Deulofeu is given a start on the left wing and Paulinho replaces Ivan Rakitic in the middle of the park.
Olympiakos, meanwhile, line up with defender Alberto Botia, who began his career at Camp Nou and also turned out for the likes of Sporting Gijon and Sevilla.
The Greek side have won their domestic League in all-but-two of the last 19 seasons but had lost three consecutive games before bouncing back over the weekend.
This is the first-ever meeting between these sides in the Champions League, although Barca boss Ernesto Valverde previously coached Olympiakos twice.
Barcelona: Ter Stegen; Sergi, Pique, Umtiti, Digne; Busquets, Paulinho, Iniesta; Messi, Suarez, Deulofeu
Subs: Semedo, Rakitic, Denis, Cillessen, Mascherano, Alcacer, Gomes
Olympiakos: Proto; Elabdellaoui, Botia, Nikolaou, Koutris; Gillet, Romao, Zdjelar; Carcela, Odjdja-Ofoe, Androutsos
Subs: Tachtsidis, Fortounis, Djurdjevic, Vukovic, Kapino, Engels, Pardo
Referee: Collum (SCO)