Barcelona start with Pedro Rodriguez, Neymar and Lionel Messi in attack for the trip to Levante.
Luis Enrique names the front three as part of an XI containing eight changes from the midweek Champions League win over APOEL.
Munir El Haddadi drops out for Pedro while the midfield is entirely new – Sergio Busquets, Ivan Rakitic and Andres Iniesta coming in for Xavi Hernandez, Sergio Roberto and Sergi Samper.
There are changes in defence too with Dani Alves the only survivor, joined by Javier Mascherano, Jeremy Mathieu and Jordi Alba.
Claudio Bravo returns in goal after Marc-Andre Ter Stegen took the gloves against the Cypriots.
Levante name what appears to be a 4-3-3 formation with Jesus Fernandez in goal and Pedro Lopez, Lukas Vyntra, Hector Rodas and Tono across the back four.
Simao Mate, Papa Diop and Victor Camarasa are inn midfield, with Victor Casadesus, David Barral and Jose Luis Morales in attack.
Levante: Jesus; Pedro Lopez, Vyntra, Rodas, Tono; Mate, Diop, Camarasa; Victor, Barral, Morales
Barcelona: Bravo; Alves, Mascherano, Mathieu, Alba; Busquets, Rakitic, Iniesta; Pedro, Neymar, Messi
Referee: Jose Gonzalez
