Xavi Hernandez will not play for Spain against Finland in their World Cup qualifier in Gijon on Friday.
La Roja are looking for the three points that could take them clear at the top of Group I.
But they will have to do so without the Barcelona midfielder, after doctors for the national team advised that the veteran's hamstring injury was too severe to play.
News from the national team camp however, suggests that he could be fit enough to face France on Tuesday.
Think you know your Spanish football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!